To get Mixtures in SAND: Raiders of Sophie, loot medical cabinets at points of interest, prioritize larger named towns for better medical-loot density, then extract safely so the Mixtures are banked.
Mixtures are a crafting and progression resource used for tech-tree upgrades, equipment, and advanced crafting. The reliable farming loop is simple: hit lootable POIs, focus on medical cabinets, and leave before the run turns into a death spiral.
Where Mixtures come from

The main place to look for Mixtures is inside medical cabinets. These cabinets can show up across lootable points of interest, including small settlements, shipwrecks, and other POIs, but the best targets are major named locations and larger towns where medical loot is more common.
You need Mixtures because several upgrades and craftables can ask for hundreds at a time. They feed progression items such as chassis parts, engines, medical supplies, and other tech-tree unlocks, so even a decent haul can disappear quickly once you start crafting.
How to farm Mixtures efficiently
STEP 1/6
Enter a lootable POI

Start your run by heading into settlements, shipwrecks, towns, or other points of interest where containers can be searched.
STEP 2/6
Prioritize larger named locations

Bigger towns and major named POIs are better farming targets because medical loot is more common there.
STEP 3/6
Search medical cabinets first

Treat every medical cabinet as a priority container, since this is the main confirmed source for Mixtures.
STEP 4/6
Check higher-tier medical cabinets

Higher-tier variants reportedly have a strong chance to contain Mixtures, though no cabinet is confirmed as a guaranteed drop.
STEP 5/6
Chain several cabinets in one expedition

Keep moving through the POI and nearby lootable spots so you open as many medical cabinets as safely possible.
STEP 6/6
Extract before you overstay

Once you have a useful haul, leave and extract so the Mixtures actually make it back to storage.
Build your route around medical cabinets, not general loot: a shorter run through several cabinet-rich buildings is better than a long sweep of random containers that ends before extraction.
Video help
Best Mixture farming targets
| Location or container | Priority | Why it matters |
|---|---|---|
| Medical cabinets | Higher | Main confirmed source for Mixtures; search these before anything else. |
| Higher-tier medical cabinets | Very high | Reportedly have a strong chance to contain Mixtures, but not a guaranteed drop. |
| Major named locations | High | Best overall targets because they tend to have more medical loot opportunities. |
| Larger towns | High | Good cabinet density makes them efficient for repeated farming runs. |
| Small settlements | Medium | Can contain medical cabinets, but usually offer fewer chances per stop. |
| Shipwrecks | Medium | Worth checking during a route, especially if you spot medical containers nearby. |
| Miscellaneous POIs | Situational | Useful only if they add more medical cabinets without pulling you too far from extraction. |
Medical cabinets are the container to care about. Other POI types can still be worth checking if they contain medical loot, but the current evidence does not confirm a fixed spawn or guaranteed Mixture container outside that cabinet-focused loop.
The best run is not necessarily the longest one. A clean route through a large town, a nearby POI, and then extraction will usually beat a greedy route that keeps you exposed after your inventory is already worth protecting.
Extracting with Mixtures safely
Picked-up loot only matters if you survive and extract. If you die before leaving the match, the Mixtures you collected during that run are not safely banked, which makes extraction part of the farming method rather than an afterthought.
Extraction uses radio towers. Look for the white circular extraction icon with a door in the middle; when you are within 200 meters of a tower, a waypoint appears. Climb the tower, activate the radio, and wait for evacuation.
After calling extraction, the dropship takes 90 seconds to arrive. Once the cable drops, you have another 60 seconds to reach it and use the prompt to ascend. In Voyage mode, radio towers remain active and do not expire, so if you miss the cable window, you can try again instead of assuming the run is dead.
Crafting uses for Mixtures
| Craft or upgrade | Mixtures needed | Other known requirements |
|---|---|---|
| MedKit | 400 | 1,500 Crown, 15x Weird Coral |
| Middling Chassis | 375 | 3,200 Crown |
| Motor-Reactor | 375 | 3,250 Crown, 4x Raw Aurogen Crystal, 15x Alloy Steel |
| Small Engine | 550 | 4,900 Crown, 5x Raw Aurogen Crystal |
| Medium Engine | 750 | 6,300 Crown, 40x Weird Coral, 360x Coral Dust |
Mixtures are not just a small consumable ingredient. Known recipe examples ask for 375, 400, 550, or even 750 Mixtures, which is why you may feel short on them even after several successful runs.
These are examples, not a complete current crafting database. Use them as the reason to keep farming Mixtures consistently, especially if you are working toward Trampler upgrades or mid-tier equipment.
Mistakes that waste Mixture runs

The biggest mistake is looting like every container has the same value. If your goal is Mixtures, medical cabinets should drive your path; random crates and general loot can wait unless they are directly on the way.
Another weak pattern is farming only tiny outposts. Small settlements can pay off, but larger towns and named POIs give you more chances to find medical cabinets before you need to extract.
The final mistake is overstaying after a good haul. Contested areas become more dangerous the longer you linger, and dying before extraction means the Mixtures do not make it back to storage.
Frequently Asked Questions
Can you get Mixtures from anything besides medical cabinets?
Medical cabinets are the main confirmed source. Mixtures may appear during looting runs, but exact drops from other containers, enemies, quests, vendors, or biome-specific routes are not verified from the available evidence.
Are Mixtures guaranteed in medical cabinets?
No. Medical cabinets are the best container to prioritize, and higher-tier variants reportedly have a strong chance to contain Mixtures, but there is no confirmed guaranteed drop.
What is the best place to farm Mixtures?
The best targets are major named locations and larger towns, because medical loot is more common there. Look for routes that let you open several medical cabinets and still reach extraction safely.
Do you keep Mixtures if you die before extracting?
No. Mixtures you pick up during a run need to be extracted safely before they are banked. If you die before extraction, that haul is lost.
Why do I need so many Mixtures?
Several useful crafts and upgrades require hundreds of Mixtures. Examples include 375 for Middling Chassis, 400 for a MedKit, 550 for a Small Engine, and 750 for a Medium Engine.