What to know
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Start at the Angel Comb and the nearby alien power plant and head roughly 30° northeast, keeping that straight bearing even when the nearby path curves.
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Axum Bacterial Culture appears as hanging slimy clusters in sludge‑filled ooze lakes; pick them by hand when they detach or float.
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There are two useful ooze pools close together: a main lake and a smaller pool slightly to the left, giving you a quick rotation for farming.
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Axum Bacterial Culture cannot be crafted and must be collected from these sludge fields to progress Axum‑linked builds.
Finding Axum Bacterial Culture in Subnautica 2 is all about hitting the right sludge zone and following a clean bearing from a known landmark. From the Angel Comb and the nearby alien power plant, you can run a straight line into the ooze fields where the cultures spawn, then use a simple two‑pool loop to farm them efficiently without exploring the entire map.
Axum Bacterial Culture details
Axum Bacterial Culture location
From the Angel Comb and the nearby alien power plant, face about 30° northeast.

And swim straight on that heading.

Ignore nearby paths that veer off to the right; continuing straight brings you directly into the sludge zone where the ooze lakes appear.

This consistent heading is the most reliable way to reach the spawn area without getting misaligned.
How to spot the correct sludge lakes

Once you reach the ooze area, look for lakes of sludge with hanging slimy clusters in the water column or near the surface. These clusters are the only visible spawn points for Axum Bacterial Culture in this region. You will see a main ooze lake and a smaller ooze pool slightly to the left; both can hold collectible clusters. Because visibility is low, move slowly and scan the vertical space around the edges of the sludge.

How to collect Axum Bacterial Culture
Swim close to hanging clusters and grab them by hand as they detach or float upward.

Some clusters may break apart without dropping an item, so it is normal to move between several clusters before collecting anything.

After clearing the main pool, move to the smaller left ooze lake and check for remaining spawns; this two‑pool loop helps you avoid waiting in one spot.

How to farm multiple cultures efficiently
Clear the visible clusters in the main ooze lake, then move over to the smaller left pool and collect any pieces there.

Alternate between the two pools while waiting for respawn, since there are only a few clusters at a time but they appear to cycle back over a short period. Axum Bacterial Culture is required for certain Axum‑linked tech and cannot be crafted.

That is why this sludge area is the only reliable source, so efficient farming here is key.

Rewards
Return to the Angel Comb / alien power plant, reset your heading to roughly 30° northeast, and follow that line back into the sludge fields to farm Axum Bacterial Culture as needed. Using both the main and left ooze pools as a rotation loop lets you steadily collect cultures for Axum‑tech progression without needing to search other biomes.