Anime Expeditions: Best AFK Tower Farming Setup for Autoplay

This is an autoplay Tower setup, not a manual clear route. A single showcase run pushed through Floor 51 with minimal input, but your result still depends on your units, traits, upgrades, and Unbound status.

Who should use this AFK Tower setup

Use this if your goal is to chain Tower floors with built-in autoplay instead of manually placing units every round. It is strongest for accounts that already have the main pieces: Shadow/Megumi, Toy Maker, Stone Alchemist, a slow, a shield breaker, and a buffer.

The setup is not about bursting a single hard floor as fast as possible. It is about making the run stable enough that autoplay can survive the early leaks, build economy, upgrade the right carry, and keep moving into the next floor.

Core AFK Tower team slots in Anime Expeditions

The team is built around Shadow/Megumi doing the heavy lifting while the other slots solve specific autoplay problems. Stone Alchemist is used as a later farm unit, Salmon Sorcerer slows enemies, Crow/Itachi breaks shields, Toy Maker cleans early leaks, and Forbidden Teacher buffs the main damage setup.

How to set up the AFK Tower autoplay run in Anime Expeditions

Configure the autoplay preset first, then use it with saved placement zones so Tower floors can advance with as little input as possible.

Choose tiny placement zones

Open autoplay settings, use Zone Position, and make the combat circle as small as possible so your units spawn where they hit the most enemies.

Disable phantom-first placement

Turn off the setting that prioritizes phantom placement so autoplay spends early money on upgrades instead of extra phantoms.

Enable Shadow/Megumi

Turn on the slot, Auto Upgrade, and Auto Abilities, then set upgrade priority to 2, placement limit to 1 if Unbound or 2 if not, and max upgrade to 10.

Enable Crow/Itachi

Enable the slot with one placement, leave auto upgrade and abilities off, and use him mainly for shield breaking.

Set Toy Maker priority

Enable Toy Maker with auto upgrade at priority 3 if she is Unbound and stable, or priority 2 if she is weaker and your run is leaking.

Loosen strict priority if needed

If neither Toy Maker nor Shadow/Megumi is Unbound, disable Strict Auto Upgrade Priority so both can receive upgrades during the dangerous early waves.

Tune Salmon Sorcerer

Place three Salmon Sorcerers and only upgrade them until they reach 5-second SPA, using max upgrade 0, 1, or 2 based on your own breakpoint.

Auto-upgrade Forbidden Teacher

Place one Forbidden Teacher and auto-upgrade her until she gives the maximum buff.

Use Stone Alchemist later

Keep Stone Alchemist as a later farm unit instead of making it upgrade priority 1.

Duplicate the preset

Make a copy of the main preset for leak-heavy stages, with Toy Maker at priority 2 and Shadow/Megumi at priority 3.

Start with the main preset

Begin the Tower floor, choose the main preset, and let autoplay place Stone Alchemist, Salmon Sorcerer, and the rest of the team in order.

Video help

Placement zones that carry across Tower maps

After the preset is ready, the most important prep is saving a placement position on each map. Anime Expeditions remembers where you set autoplay for that map, so you only need to visit each relevant story or Tower layout once and define the circles.

Use a small combat circle where your slow, carry, shield breaker, and support can all affect the lane. Put the farm circle where Stone Alchemist can be placed consistently without dragging your combat units away from the best choke point.

For early Tower floors with Unbound characters, the combat circle can sit near the front of the path so Shadow/Megumi kills quickly and Toy Maker catches leaks. Repeat the same setup pass for each map in the rotation so autoplay does not need a fresh placement decision every floor.

Gameplay toggles for hands-off Tower chaining

Turn on Auto Next and Auto Start in gameplay settings before you begin the run. These toggles are what let the game move from one cleared Tower floor into the next without waiting for a manual click.

If you are leaving attempts running for a long session, also enable Auto Retry. That does not make the build stronger, but it prevents one failed overnight attempt from ending the farm completely.

Some older AFK farming routes also mention using Repeat Stage after enabling Auto Upgrade, especially for Expedition-style payload defense. For this Tower route, the useful shared idea is the same: use the game’s own repeat and autoplay tools first, then only add outside input tools if you accept the extra risk.

AFK reliability and macro risk

The built-in autoplay button can turn off after a while, which is the main reliability problem for long Tower sessions. The showcased workaround is an auto-clicker aimed at the autoplay button, using a short click interval so the button keeps being reactivated during the run.

That workaround is also the riskiest part of the setup. External macros, scripts, executors, and auto-farm tools are treated inconsistently across player guides, and policies can change, so the cleaner approach is to rely on Auto Next, Auto Start, Auto Retry, saved placement zones, and in-game autoplay whenever possible.

If you still use an auto-clicker, keep the setup simple: click only the autoplay button, avoid scripts or executor-based farming, and do not build the run around actions the game’s own autoplay cannot already perform.

Post-Floor-50 Tower team variants

After Floor 50, Cuber becomes the main support upgrade over Forbidden Teacher. Cuber works especially well with this autoplay method because the whole setup is already packed into one tight circle, letting his cubes reach the units that need the buff.

Cuber also brings extra stun value, so the carry slot can be more flexible. Shadow/Megumi is still excellent, but Elf Mage is a supported swap idea when you want a different full carry that can benefit from Cuber’s range-based support.

For the smoothest Tower grind, aim for Unbound on the main damage and leak-control pieces first. Crow/Itachi and Cuber do not need Unbound for their listed jobs, but Toy Maker and Shadow/Megumi gain much more from it.

Farming priorities outside Tower

Outside Tower, the best farming rule is simple: run the fastest stage your team can auto-clear consistently, not the hardest stage you can barely finish. Stable clears scale better over long sessions because failures, leaks, and stalled repeats erase the value of a bigger reward screen.

Older farming numbers from before Update 0.5 are useful only as starting points. Check the current in-game rewards before committing a night of farming, especially for Gem routes, Gold routes, Mastery stages, Challenges, and Expedition payload defense.

Related Anime Expeditions guides

• Anime Expeditions Best Team: Meta Picks, Beginner Setup, and Raid Swap
• Anime Expeditions Gowther Megumi Loop: Effects, Requirements, and Setup
• Anime Expeditions Villain Invasion Illusion Crow: Cost, Stats, and Tips
• Anime Expeditions Crow Relic Loop: Best Method, Rewards, and Setup