What to know
- Handgun ammo is made using a minimal combination of one scrap plus infected blood.
- You must unlock the handgun ammo recipe by analyzing a specific purple blood specimen in the blood‑lab machine.
- The blood collector tool, which generates infected blood, is story‑flagged and cannot be skipped.
- Once unlocked, you can craft multiple handgun bullets at once from the crafting screen whenever you have spare scrap and blood.
In Resident Evil Requiem 9, natural ammo drops are limited, so crafting handgun ammo becomes essential for surviving longer stretches of combat. The system ties directly into the blood‑collector mechanic, where you convert infected blood into bullets instead of relying only on what you scavenge from enemies or supply boxes.
| Aspect | Detail |
|---|---|
| Ammo type | Handgun ammo (standard pistol rounds) |
| Crafting station | Crafting menu accessible from the pause/interface screen |
| Main materials | Scrap ×1, infected blood ×40 (per batch) |
| Recipe unlock method | Analyze a purple blood specimen in the blood‑lab machine |
| Blood source | Blood collector tool filled from infected samples |
| How often you can craft | As often as you have scrap and blood, no cooldown |
Locations
The handgun ammo‑related tools and machinery cluster around the East Wing of the Care Center, especially the blood room where you first acquire the blood collector. Nearby you will find a locked machine or analyzer that must be used to run the purple specimen and unlock the handgun‑ammo recipe; lockers and storage in that area also contain an early scrap item to help you test crafting.

How to unlock the handgun ammo recipe
Step 1: Reach the blood lab
Advance through the story until you reach the blood lab in the East Wing, where crafting‑related machines begin to appear. This area is part of the main path, so you will pass through it without needing to go off‑route.

Step 2: Pick up the blood collector
In the same room where the blood‑related machines are located, you will automatically pick up the blood collector as part of the story. This device is required later to generate infected blood, so you cannot skip this step.
Step 3: Get the purple blood specimen
Locate a specific purple‑colored blood specimen in the lab; this is the key item that unlocks handgun ammo and a few injector recipes.

The specimen will be placed near the analyzer machine or in an adjacent container, clearly marked as a usable item.

Step 4: Analyze the specimen
Interact with the blood‑lab machine.

Select the purple specimen to run an analysis.

The interface will show you a node‑style grid where you need to toggle the right nodes so that all atom‑like spots light up red; it’s one of the blood specimen puzzles. Click on the middle square to solve this one.

Step 5: Confirm the recipe unlocks
After the analysis completes, the system will register that you have unlocked the handgun ammo crafting option.

An indicator or recipe icon will appear in your crafting menu, showing that you can now combine scrap and infected blood into handgun bullets.

How to gather the crafting materials
Step 1: Collect scrap
Scrap is a common crafting material that appears in lockers, shelves, and containers throughout the Care Center and later areas.

In the blood‑lab room itself, there is typically at least one scrap item inside a nearby locker, which you can grab immediately after picking up the blood collector.

Step 2: Fill the blood collector
Use the blood collector on infected bodies or environmental samples to generate infected blood.

The tool fills a gauge, and once it reaches a set amount, you can use that stored blood in the crafting menu.

Step 3: Keep scrap and blood stocked
Always keep a small reserve of scrap and blood, since handgun ammo can be burned through quickly in close‑quarters encounters. If you run low on scrap, recycle broken knives or other scrap‑based items where possible, so you can convert them back into bullets in emergencies.
Step 1: Open the crafting interface
Bring up the game’s menu or pause screen and navigate to the crafting tab.

The handgun‑ammo option will now appear, usually labeled with an icon that matches your pistol’s ammunition.
Step 2: Select the handgun ammo entry
Highlight the handgun ammo entry, which will show the required materials: one scrap and a set amount of infected blood per batch. The exact number of bullets produced per batch is fixed, so you do not need to adjust a quantity slider.
Step 3: Confirm the craft
Confirm the crafting action when you have at least one scrap and the required blood ready. The system will consume the materials and add the corresponding handgun ammo to your inventory, instantly replenishing your pistol rounds.

Step 4: Repeat as needed
Whenever you restock scrap or fill the blood collector again, return to the crafting menu and repeat the same process. Over time, shifting from purely scavenging for bullets to crafting them becomes a core part of your resource loop.
Rewards table for crafting handgun ammo
| Resource invested | benefit |
|---|---|
| 1 scrap + 40 infected blood | 10 handgun ammo rounds added to inventory |
| Filled blood collector | Multiple future ammo batches without needing to stop and scavenge mid‑area |
| Re‑using scrap from knives | Extra ammo from otherwise disposable melee tools in tight spots |
| Keeping a blood stockpile | Fewer forced retreats to safe rooms or supply boxes for basic handgun ammo |
Mastering handgun ammo crafting in Resident Evil Requiem 9 means you can extend your firefights and stay aggressive without constantly worrying about running dry. By treating scrap and infected blood as your primary ammo currency from the early East Wing onwards, you will find yourself far more self‑sufficient throughout the rest of the campaign.