Resident Evil Requiem: All Blood Specimen Locations and Puzzle Solutions Guide Including Insanity Difficulty Challenges

What to know

  • Four Blood Specimens exist in Resident Evil Requiem: Denatured, Converged, Reversible on standard difficulties, plus Polymerized on Insanity.

  • All are found in Care Center area; use ID Wristband Level 1 for two of them.

  • Analyze at Blood Lab machine by clicking cube nodes to turn all atoms into spheres.

  • Rewards unlock key crafting recipes like ammo and injectors.


Blood Specimens power up your crafting in Resident Evil Requiem by analyzing unique atom structures at dedicated machines. These puzzles challenge you to transform nodes efficiently within move limits, mainly in the Care Center’s East Wing.

Blood Specimen Location Difficulty Min Steps Crafting Unlocks
Denatured Blood Lab All 1 Handgun Ammo, Hemolytic Injectors
Converged Closet via Waiting Room Level 1 door (Ward Office) Casual/Standard 2 Med Injectors, 12.7x55mm Ammo
Reversible Blood Lab side room via Level 1 door All 4 Steroids, Stabilizers
Polymerized Closet via Waiting Room Level 1 door (Records Room) Insanity 3 R.I.P. Knife, Handgun Ammo x30
 

Care Center locations for Blood Specimens

Access most Blood Specimens in the Care Center’s East Wing, centered around the Waiting Room, Blood Lab, and adjacent locked rooms.

Grab the ID Wristband Level 1 from a corpse on the second floor hallway past Lead Researcher’s Office—lure away or defeat the pursuing flesh monster first by running downstairs to the Waiting Room.

Use it on Level 1 doors: one opens the closet off Waiting Room for Converged (or Polymerized on Insanity), another unlocks the Blood Lab side room for Reversible. Denatured sits openly in the main Blood Lab.

How to find ID Wristband Level 1

Head to East Wing second floor via stairs from Waiting Room.

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Approach end of hallway beyond Lead Researcher’s Office door. Spot the corpse with wristband.

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Grab the ID Wristband quickly before the monster emerges. Run downstairs left to Waiting Room, clear zombies, wait for patrol, then retry if needed.

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How to solve Denatured puzzle

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First, grab the specimen placed before the computer.

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Interact with analyzer in Blood Lab holding Denatured specimen.

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Click the left middle square to transform all connected cubes to spheres in one move.

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How to solve Converged puzzle

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Use analyzer after picking Converged from Waiting Room closet (Casual/Standard).

Image credit: Capcom / Via: YouTube – GosuNoob
Step 1

Click top middle square.

Image credit: Capcom / Via: YouTube – GosuNoob
Step 2

Click second square from bottom to finish.

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How to solve Reversible puzzle

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Analyzer is found in Blood Lab after accessing the side room with wristband.

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Step 1

Click bottom-left corner square.

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Step 2

Click middle square.

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Step 3

Click top right square.

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Step 4

Click second square from the topmost one.

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How to solve Polymerized puzzle on Insanity

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Found in Records Room closet; use same Waiting Room Level 1 door.

Image credit: Capcom / Via: YouTube – GosuNoob
Step 1

Click middle left square.

Image credit: Capcom / Via: YouTube – GosuNoob
Step 2

Click middle right square.

Image credit: Capcom / Via: YouTube – GosuNoob
Step 3

Click middle bottom square.

Image credit: Capcom / Via: YouTube – GosuNoob

Blood Specimen rewards table

Specimen Rewards unlocked
Denatured Handgun Ammo, Hemolytic Injectors
Converged Med Injectors, 12.7x55mm Ammo
Reversible Steroids, Stabilizers
Polymerized R.I.P. Knife, Handgun Ammo x30
 

Prioritize wristband early to hit all four specimens. Reset analyzer if moves exceed minimum to avoid failure. Craft rewards immediately for survival edge against tougher foes.

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